Oxotremorine M iodide

Research use only, not for human use.

Oxotremorine M iodide is a potent and non-selective agonist of muscarinic acetylcholine receptor (mAChR).

Oxotremorine M iodide is a potent and non-selective agonist of muscarinic acetylcholine receptor (mAChR).(In Vitro):Oxotremorine M iodide robustly elicits a phosphoinositide response (EC50 = 0.22 μM).?Oxotremorine M iodide shows EC50s of 0.36, 0.52, 1.62, and 1.48 μM for wild-type, M2, M3, and M2/M3 knockout mice, respectively.?Oxotremorine M iodide (0.1-30 μM) dose-dependently inhibits KCNQ2/3 currents.(In Vivo):In male Sprague-Dawley albino rats, Oxotremorine M iodide (0.5 mg/kg; s.c.) increases DA release in the medial prefrontal cortex without affecting the nucleus accumbens.

Oxotremorine methiodide

Others

Other Targets

5-HT1; 5-HT2; 5-HT4

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3854-04-4

322.2

C11H19IN2O

>98% (HPLC)

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[I-].C[N+](C)(C)CC#CCN1CCCC1=O

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(-20℃)

With Ice Pack

≥ 2 years